Repatha®

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HE COUNTS
ON YOU
Because you help to protect him
from another life-changing CV event1,2

Approved in the EU since 20153

Repatha® is a groundbreaking medicine first approved in 2015 for the reduction of LDL-C as an adjunct to statins3 and approved in 2018 for reduction of cardiovascular risk in people with a history of heart attack, stroke or peripheral artery disease.4
View the full Repatha® therapeutic indications

PCSK9 inhibitors endorsed in 2019 ESC/EAS Dyslipidaemia Guidelines5

The 2019 update of the ESC/EAS dyslipidaemia guidelines support a “lower is better” approach through more intensive reduction of LDL-C across CV risk categories.5
PCSK9 inhibitors like Repatha® are endorsed as the standard of care with the highest level of recommendation (I A) for very-high-risk secondary prevention patients who have not achieved their LDL-C goals on maximum tolarated statin and ezetimibe therapy.5

Discover the 2019 dyslipidaemia guidelines

PROTECT YOUR PATIENTS
Repatha® delivers 25% CV risk reduction in patients with a recent MI6
WE ARE OPEN!
Step inside our Virtual Booth and explore the next level of post-MI care with Repatha®
LISTEN TO VOICES THAT COUNT
Explore podcasts and interviews with cardiology experts on key topics in LDL-C control

*
25% RRR reported as the key secondary endpoint: composite of cardiovascular death, MI or stroke. HR: 0.75; 95% CI: 0.62-0.91; p=0.003. ARR: 3.2%; 95% CI: 1.2-5.2.
ACS = Acute coronary syndrome; ARR = Absolute risk reduction; CV = Cardiovascular; EAS = European Atherosclerosis Society; ESC = European Society of Cardiology; EU = European Union; EVOPACS = EVOlocumab for Early Reduction of LDL-cholesterol Levels in Patients With Acute Coronary Syndromes; LDL-C = Low-density lipoprotein cholesterol; MI = Myocardial infarction; PCSK9 = Protein convertase subtilisin/kexin type 9; RRR = Relative risk reduction.
  1. Sabatine MS, et al. Circulation. 2018;138:756-66.
  2. Repatha® (evolocumab) Summary of Product Characteristics. Last revised: 31 March 2021.
    Available at: https://www.ema.europa.eu/en/documents/product-information/repatha-epar-product-information_en.pdf. Accessed: June 2021.
  3. EMA Press release 22/05/2015. Available at: https://www.ema.europa.eu/en/news/first-class-treatment-lower-cholesterol. Accessed: June 2021.
  4. EMA Summary of opinion 22/03/2018.
    Available at: https://www.ema.europa.eu/en/documents/smop/chmp-post-authorisation-summary-positive-opinion-repatha-ii-17-g_en.pdf. Accessed: June 2021.
  5. Mach F, et al. Eur Heart J. 2020;41(1):111-188.
  6. Gencer B, et al. JAMA Cardiol. 2020;5(8):1-6.

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By clicking the ‘DOWNLOAD’ button below you will immediately begin downloading the Reporting Systems Appendix
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